Our new Clear+ tissue clearing method is the sole strategy that delipidates samples without improve in morphology and with minimal impact on structural integrity.
Megatome is a vibrating microtome created to area a wide selection of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With large blade vibrating frequency and minimized blade deflection, Megatome allows substantial-throughput tissue sectioning with uniform floor profile, and minimal tissue damage and information loss.
Antibodies may well acquire months to diffuse by only some millimeters of tissue, that has a steep labeling gradient from floor to Main.
Megatome is created for precision: the blade vibrates at a better frequency and larger amplitude assortment than other microtomes, and includes a special deflection Handle mechanism.
SE works by using a rotational electrical discipline to disperse very electromobile molecules (like antibodies or surfactant micelles) all through a porous sample without harming electrically billed buildings in the tissue. This permits 2-4 working day clearing of intact organs,
Our preformulated EasyIndex Alternative raises and homogenize the refractive index of delipidated tissue samples, rendering them thoroughly clear. This enables light penetration into your sample and makes certain the acquisition of large-resolution, in-concentrate graphic knowledge.
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eFLASH is usually a swift tissue labeling method which allows for uniform complete-organ staining in twenty rounds of labeling.
The SmartSPIM light-weight sheet microscope supplies unparalleled resolution and acquisition velocity through intact tissue volumes, while its modular layout enables you to up grade and customize particular person parts.
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Leverage the Crystal clear+ tissue clearing process, together with megatomi.com eFLASH and patented stochastic electrotransport technologies, to speedily distinct and label entire organs. Crucial highlights and capabilities involve:
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